Sleep Deprivation Device

Vendor: SANS

Type: Animal Research Equipment

Sleep deprivation (SD) impairs spatial, emotional, and working memories, and augments anxiety-like behaviors. The Sleep Deprivation Device is an automated ch... ... Read More

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Overview

Feature

Highlights

Applications

Specifications

Order Information

Literature

FAQ

Customer Review

overview

Sleep deprivation (SD) impairs spatial, emotional, and working memories, and augments anxiety-like behaviors. The Sleep Deprivation Device is an automated chamber that can be used for sleep deprivation and sleep fragmentation studies in rodents, provides movement at programmed intervals to prevent REM sleep. It gently and safely keeps rodents awake by using the rotating bar to touch the animals. With further integration capabilities for EEG/EMG, optogenetics, fiber photometry, and video tracking systems, sleep deprivation device plays vital role in exploring circadian rhythms, sleep disorders, and neuropsychological dysfunctions.

The sleep deprivation device for rat and mouse consists of a clear acrylic chamber atop a motor and screen to set time and rotations of a bar inside the chamber to prevent the rodent from sleeping in a safe way. Food and water apparatuses are available to allow long-term experimentation. Our rat and mouse sleep deprivation device equips with a circadian rhythm light control system, and it can be used for optogenetic experiments and calcium ion imaging experiments.

Features & Benefits

Programmable Rotating Bar System

Adjustable speed (1–20 cm/s), direction (CW/CCW/random), and pause intervals (0–240s)

External Trigger Interface

Compatible with Optogenetic, Calcium ion imaging, and EEG setups

Scheduled Automatic Start/Stop

Includes circadian rhythm light control for better sleep deprivation effects

AI-Integrated Interface

Real-time control and automatic recording via 5” touchscreen; intelligent sleep state detection with camera

Dual Use

Supports total deprivation, REM-specific, and intermittent sleep fragmentation protocols

Ultra-Quiet Operation

Noise level <30 dB ensures minimal stress to animals

Housing Chamber

Modular design supports 8–12 mice or 4–6 rats; food and water access included

Highlights

Fully Automated Protocols

Eliminates operator error and manual handling

Low Stress to Subjects

Gentle rotating instead of forced locomotion

Compatible with High-Level Analysis Tools

Supports EEG/EMG, optogenetics, and fiber photometry

Supports Long-Term Studies

Food and water supplied in the unit

Wide Application Versatility

Suitable for behavioral, metabolic, and pharmacological research

Applications

Circadian Rhythm Research: Study phase shifts, sleep-wake cycles, jet lag models

Sleep Disorders Modeling: Investigate insomnia, REM behavior disorder, narcolepsy

Metabolic Studies: Explore connections between sleep and obesity, glucose tolerance, insulin resistance

Neurological & Psychological Research: Assess sleep’s role in depression, anxiety, memory loss, PTSD, and cognitive decline

Pharmacology & Drug Screening: Evaluate sedatives, stimulants, and cognitive enhancers under sleep-deprived conditions

Specifications

Operation

Customized schedule	Total running time, scheduled start, rotation period, custom periodic breaks of 0~99999 s
Experiment duration	1~9999 min
Display	Easy to operate capacitive 5 inch HD LCD screen with high response speed
Period range (rotation-stop)	0 s ~ 99999 s
Time display precision	1 second
Rotation mode	Clockwise, counterclockwise, alternate, and random
Rotation speed	0.1-100 RPM, step 0.1 RPM
Rotation bar diameter	8 mm
Rotation bar height adjust	1.8 cm
Motor noise	Quiet motor at <30 dB

Data Analysis

Control	LCD screen & computer software control
Configurations	Saved on the device
Data export	Exportable to PC via USB port; no software or PC required
Data output	Total Circle, Total Time, Run Time, Rotation Time, Interval Number, Rotation Number, Interval Time, etc.

Size

Chamber dimensions	(D) 30 cm × (H) 25 cm	Weight: 10 kg
Controller apparatus	(L) 30 × (H) 32 × (W) 9 cm	Weight: 5.8 kg

Order Information

Item No.	Product Description
SA109	Sleep Deprivation Device for Rat and Mouse
SA109 Pro	Sleep Deprivation Device for Rat and Mouse (Intelligence version)

literature

International Journal of Molecular Sciences

Caffeine-Induced Sleep Restriction Alters the Gut Microbiome and Fecal Metabolic Profiles in Mice

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The Innovation

Sustained microglial activation and accelerated elimination of dendritic spines during acute sleep deprivation and restoration

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Kidney International – Involvement of circadian clock protein PER2 in controlling sleep deprivation induced HMGB1 up-regulation by targeting p300 in the cortex

Disrupting circadian control of autophagy induces podocyte injury and proteinuria

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Frequently Asked Questions

What is the difference between the standard sleep deprivation device and Pro version?

The Pro version has a feedback system using a camera; rotation occurs when rats/mice stay still. Pro version operates one mouse/rat at a time, while standard device supports multiple animals.
Can this sleep fragmentation device connect to EEG/camera set-up to send trigger pulses?

Yes, both standard and Pro versions are equipped with TTL external trigger interfaces for Optogenetic, Calcium ion imaging, and EEG.
Can I send TTL pulses through a BNC cable to trigger individual rotations?

Yes, TTL trigger has 2 activations: one for starting the experiment and one for ending the sleep deprivation model.
How customizable are the rotations triggered by such a pulse?

3.3V–5V can be used as the trigger through a BNC cable; pulse width should be ≥ 50ms.
Is there a hole on the lid to allow cables being connected to the mouse?

Yes, there is a hole on the sleep deprivation chamber lid.