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FR-21 Tricolor Multichannel Fiber Photometry System
FR-21 Tricolor Multichannel Fiber Photometry System
FR-21 Tricolor Multichannel Fiber Photometry System

FR-21 Tricolor Multichannel Fiber Photometry System

Vendor: RWD Life Science
Type: Neural Circuit
The RWD Fiber Photometry System records changes in neuronal fluorescence intensity to monitor population activity in specific brain regions. This fiber photo... ... Read More
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$19,542.40 $24,428.00 Save $4,885.60

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Delivery timelines will be provided with your quote

Standard lead time varies by product availability (in-stock items usually 1–3 business days, custom/backordered items 7–21 business days).

90-day return policy

90-day return policy

Eligible items may be returned within 90 days after delivery, subject to our Return Policy.

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Final delivery schedules and pricing are subject to confirmation in your official quotation. Customs policies may also impact the total cost. Contact us for your best quote.

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overview

The RWD Fiber Photometry System is a high-performance fiber photometry system designed for precise and reliable monitoring of neuronal activity. Using changes in fluorescence intensity, it enables long-term, stable recording of neurons in freely moving animals, helping researchers investigate correlations between neural activity and behavior in fiber photometry mice studies.

The R821/FR-21 multi-channel fiber photometry system supports multiple excitation wavelengths (410 nm, 470 nm, 560 nm), with 410 nm used as a reference to eliminate noise. It can record signals from green indicators like GCaMP and dLight, red indicators such as RCaMP or jrGECO1a, and various neurotransmitter probes. With up to 9 channels, this multi fiber photometry system allows simultaneous monitoring of multiple brain regions and is compatible with optoelectronic equipment for versatile experimental setups.

Key features of the RWD fiber photometry system include:

  • Multi-channel recording for simultaneous monitoring of up to 9 brain sites
  • Tricolor excitation wavelengths: 410 nm reference, 470 nm green, 560 nm red
  • Compatible with optogenetics to combine recording and stimulation at the same site
  • Dual detectors for independent, sequential detection to avoid signal interference
  • Professional acquisition and analysis software with live display, heat maps, and peak statistics
  • Flexible acquisition modes including continuous, interval, trigger-based, delayed, and timed recordings

Reliable, flexible, and easy to use, the RWD fiber photometry system provides a versatile solution for advanced neural circuit research in mice and other animal models.

Features & Benefits

One-Click Graphs

Automatically generates fluorescence heatmaps, curve plots, and animal trajectory graphs for fast and intuitive visualization.

High-Sensitivity Signal Acquisition

Detects weak signals at the picowatt level, ideal for monitoring axons and glial activity.

Professional Data Analysis

Offers comprehensive pre-processing, event refinement, multi-dimensional analysis, and flexible data export options.

High Integration

Built-in optogenetic interface enables simultaneous stimulation and recording at the same site.

Stable Long-Term Performance

Supports over 500 hours of continuous acquisition, suitable for long-term experiments such as sleep studies.

Strong Expansion Capability

Four digital input/output interfaces and excitation light combination modes allow up to 9-channel simultaneous acquisition.

Highlights

Three kinds of excitation light sources, that are 410nm、470nm and 560nm, are respectively used for excitation of reference, green fluorescence and red fluorescence;

Support up to 9 channels, suitable for simultaneous experiment of multiple animals or multiple brain locations;

Dual highly sensitive detectors enabling independent and sequential detection to avoid interference of fluorescence excitation and detection, acquiring more accurate signals;

Professional acquisition and analysis softwares are flexible and easy to operate with data processing functions available. No matlab programming is required;

Supports multiple acquisition modes including continuous acquisition, interval acquisition, acquisition upon trigger, delayed acquisition and timing acquisition;

Live display of DeltaF/F acquisition to check scale of signal changes during acquisition;

Customized adjustment of output signal parameters, easily trigger and control external excitation equipment to achieve closed-cycle control of excitation and recording;

Applications

Ca2+ and Neurotransmitter sSgnal Detection

Neural Circuit Functionality Study

Mechanisms of Neurological Diseases Exploration

New Fluorescent Sensor Probes Development

Optical Principle Experiment

Specifications

Item Quantity Description
Fiber Photometry Main Device 1 Includes: Host, power cord, 3 USB cables, USB expansion interface, software U disk
Computer 1 Includes pre-installed software, I5-10500H/16G/500G/WIN10 (1920×1080)
Optical fiber 1 Low Autofluorescence Fiber-optic Patch Cords 200um/0.37NA/2m, Φ1.25mm or Φ2.5mm
Fiber Cannula sleeves 1 Black Ceramic Sleeves, Φ1.25mm or Φ2.5mm
Behavior Camera 1 Record video of animal behavior and identify animal tracks, USB3.0, 3M
Behavior Camera bracket 1 Adjustable height range 0.8–1.5m, Rotation Angle 360°
Photobleaching device 1 FC/PC Patch Cord photobleaching machine (R810-1)
U disk 1 Software key (Not for analysis function)

Order Information

Parameter Specification
Wavelength of excitation light R811: 410nm 470nm
R821: 410nm 470nm 560nm
Power Min 0μW, Max≥100μW, adjustable with an accuracy of 0.1μW
Number of channels 9
Frame rate of fluorescent sampling Max 250fps
Digital signal interface 4 Input 4 Output
Signal output Output frequency 0-500Hz, adjustable output pulse width and duration
Marking Manual marking (10), automatic marking (4), ROI marking (9)
Behavior camera 1920*1080 (30fps), 1280*720 (60fps)
Switchable among multiple frame rates of resolution