RWD LSCI ZW Laser Speckle Contrast Imaging System

RWD LSCI ZW Laser Speckle Contrast Imaging System

Vendor: RWD Life Science

Type: In Vivo Imaging Systems

The RFLSI-ZW Laser Speckle Contrast Imaging System is a high-performance laser speckle contrast imaging (LSCI) system for microcirculation research, enabling... ... Read More

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$54,000.00

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90-day return policy

Eligible items may be returned within 90 days after delivery, subject to our Return Policy.

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Overview

Feature

Advantages

Highlights

Applications

Specifications

Resources

Case Study

Literature

Customer Review

overview

RFLSI-ZW Laser Speckle Contrast Imaging System is a high-performance laser speckle contrast imaging (LSCI) system for microcirculation research. Using advanced laser speckle contrast imaging LSCI technology, this laser speckle contrast imager enables non-invasive, real-time blood flow imaging with high image quality, fast full-field frame rates, and a large imaging field. Designed for stable and reliable operation, the RFLSI-ZW laser speckle contrast imaging system is suitable for both human and animal tissue blood flow measurement and microvascular analysis.

Key performance advantages of the RFLSI-ZW laser speckle contrast imaging system include:

Large imaging field size for comprehensive microcirculation observation
High spatial and temporal resolution for clear blood flow visualization
Fast full-field frame rate for real-time imaging
Non-contact, non-invasive measurement process
Reliable performance for human and animal tissue blood flow studies

As an advanced laser speckle contrast imaging system, RFLSI-ZW provides researchers with an efficient and accurate solution for microvascular and microcirculation analysis.

Features & Benefits

Non-Contact & Contrast-Free Measurement

Enables non-contact blood flow measurement without contrast agents, reducing experimental complexity while preserving tissue integrity.

High Optical Resolution

Up to 3.9 μm/pixel resolution for clear visualization of fine tissue structures and microvascular details.

High-Speed Full-Field Imaging

Supports full-field imaging up to 100 fps, capturing dynamic blood flow changes in real time.

Wide Imaging Field

Imaging range from 0.57 × 0.75 cm² to 22.5 × 30 cm², suitable for diverse microcirculation research needs.

Fast & Precise Focusing

Combines automatic and manual focus functions for efficient and accurate imaging on various tissue surfaces.

Optimized Optical Filtering

Advanced lens assembly filters ambient and reflected light to ensure stable imaging and consistent data quality.

Class 1 Laser Safety

Measurement and indicating lasers comply with Class 1 safety standards for safe and user-friendly operation.

Reliable System Calibration

Supports precise calibration with a dedicated Calibration Box to maintain measurement accuracy.

Flexible External Integration

Trigger In/Out BNC connections enable synchronized communication with external experimental devices.

Unlimited Software Installation

Analysis software can be installed on unlimited PCs, supporting collaborative research workflows.

Advantages

Versatile, Non-Invasive Imaging

The system supports imaging of exposed tissues, including skin and surgically exposed areas, across multiple species. Non-contact, contrast-free measurement simplifies experimental workflows while preserving tissue conditions.

High-Speed and High-Resolution Performance

Equipped with a built-in CMOS global shutter camera, the system achieves fast data acquisition with an optical resolution of up to 3.9 μm/pixel and a maximum full-field frame rate of 100 fps, enabling real-time visualization of dynamic blood flow.

Wide Imaging Field with Flexible Zoom

A motorized 10× optical zoom and auto focus allow imaging sizes ranging from 0.57 × 0.75 cm² to 22.5 × 30 cm², covering both micro- and macro-scale research needs in a single all-in-one imager.

Efficient Focusing and Optimized Optics

Fast auto focus combined with fine manual adjustment improves focusing efficiency on various tissues, while the optimized lens assembly effectively filters ambient and reflected light for stable image quality.

Safe, Stable, and Reliable Operation

Class 1 measurement and indicating lasers ensure safe use without eye protection. Dedicated laser stability hardware supports consistent measurements over minutes, hours, and days, with calibration available at any time via a Calibration Box.

Easy Integration and Software Flexibility

Trigger In/Out BNC connections enable synchronization with external devices, and the analysis software can be installed on unlimited PCs, supporting collaborative and multi-user research environments.

Highlights

HD image & Video

2064*1544 high-resolution images; Optimize imaging details through algorithmic image stacking.

Accurate Data

Precise temperature control; Self-calibration program; Multiple optical lens coatings.

Large imaging area

Image size ranges from 5.7mm x 7.5mm to 225mm x 300mm； Motorised 10x optical zoom and auto focus.

Fast imaging

A high-speed camera (up to 100 FPS)； Fast data transfer with USB3.0.

Easy to use

No contrast agent required; Flexible stand and cart options; BNC communication interface.

Safe Laser

Class 1 per IEC 60825-1:2014 – Safe to use without eye protection.

Applications

Cerebral Blood Perfusion Monitoring

MCAO Model Assessment

Hind Limb Ischemia

Septic Shock

Tumor Angiogenesis

Kidney Blood Flow Monitoring

Thrombus

Chicken Chorioallantoic Membrane Assay

Skin Allergies

Laser Therapy

Eczema

Diabetic Foot

Specifications

Parameter	Description
Resolution	Max Camera Resolution: 2064 × 1544 pixels Best Resolution: 3.9 μm/pixel
Image	Flux / Gray / Intensity / Color / Overlay
Measurement Laser	785 nm, Class 1
Indicating Laser	650 nm × 2, Class 1
Focus	Auto / Manual (Fine Focus)
Trigger	2 × BNC
Image Size	0.57 × 0.75 – 22.5 × 30 cm²
Max Frame Rate	100 fps (Full Field)
Zoom	10×
Working Distance	10 – 40 cm (Continuous)
System Calibration	Calibration Box
Software	Acquisition Software and Analysis Software

Certificate

For Research Use Only (RUO). Not for use in diagnostic procedures or patient testing.

Case Study

Explore more about our latest projects and innovations through our articles, events, webinars, success stories, and in-depth insights.

User Case: Laser Speckle Imaging System (LSCI),measure blood flow in cerebral arteries via a cranial window in anesthetized mice, to corroborate an in vivo physiological role for pS1928 upon HG

JIANXIN WANG

Nov 16, 2025

User Case: Laser Speckle Imaging System (LSCI),measure blood flow in cerebral arteries via a cranial window in anesthetized mice, to corroborate an in vivo physiological role for pS1928 upon HG

Constraints and Considerations in Laser Speckle Contrast Imaging

HeQiyue

Dec 12, 2025

Constraints and Considerations in Laser Speckle Contrast Imaging

literature

RWD Laser Speckle Contrast Imaging System has contributed to publishing more than 100 reputed research papers in journals like Nature Communications, Blood, Circulation Research, Brain, Diabetes, and Theranostic. The paper list we collect contains about 18 research topics such as Cerebral Ischemia & Ischemic Stroke, Traumatic Brain Injury (TBI), Angiogenesis, Diabetes, Alzheimer’s Disease, Wound Healing, Limb Ischemia, etc.

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