BioPerfectus Coxsackievirus A6 and A10 Real-Time PCR Kit

Coxsackieviruses belong to the Picornaviridae family, genus Enterovirus, and are a group of human enteroviruses. They are positive-sense single-stranded RNA viruses with an icosahedral capsid composed of proteins. Coxsackieviruses are divided into two subgroups, A and B: Coxsackievirus A includes multiple serotypes, while Coxsackievirus B includes six serotypes (1–6).

Hand, foot and mouth disease (HFMD) is an acute infectious disease caused by enteroviruses and most commonly occurs in preschool children, particularly those under 5 years of age. Clinical manifestations include maculopapular rash and vesicular lesions on the hands, feet, and mouth. In rare cases, severe complications such as meningitis, encephalitis, encephalomyelitis, pulmonary edema, and circulatory disorders may occur. HFMD is most commonly associated with Coxsackievirus A16 and Enterovirus 71, while Coxsackievirus A6 and A10 are also known to cause outbreaks. Transmission primarily occurs via the gastrointestinal tract, respiratory tract, and close contact.

This kit is a molecular biology reagent based on real-time PCR technology, designed for the detection of Coxsackievirus A6 (CA6) and Coxsackievirus A10 (CA10) nucleic acids in throat swab samples from infants and children.

For Research Use Only (RUO). Not for use in diagnostic procedures or patient testing.