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Hand-foot-and-mouth disease (HFMD) is an acute infectious disease caused by enteroviruses. It is most common in preschoolers, especially those under three years old. It is mainly transmitted through close contact with the infected and subclinically infected individuals and gets into the body through the respiratory tract and gastrointestinal tract. The most common symptoms of the disease include macules, papules and herpes on hands, feet, and mouth. A small number of patients may suffer from meningitis, encephalitis, encephalomyelitis, pulmonary edema, and circulatory disorders. CoxA16 and EV71 are the major causative agents of HFMD, and the disease-induced brainstem encephalitis and neurogenic pulmonary edema are the leading causes of death.
The CoxA16 & EV71 Real Time PCR Kit is intended for the in-vitro qualitative detection of Coxsackievirus A16 (CoxA16) and Enterovirus 71 (EV71) RNA which is obtained from human throat swabs.
CE
| Target | CoxA16, EV71 |
| Clinical Performance |
Sensitivity: 98.6% (CA16), 97.6% (EV71) Specificity: 98.1% (CA16), 99.7% (EV71) |
| Limit of Detection | 2.0 × 10-2 CCID50/0.1 mL |
| Assay Runtime | 115 min |
| Storage Temperature | -20 ± 5°C |
| Sample Type | Throat swab |
| Catalog | Product | Package |
| JC20203NW-25T | CoxA16 & EV71 Real Time PCR Kit | 25 Tests/Kit |
| JC20203NW-50T | CoxA16 & EV71 Real Time PCR Kit | 50 Tests/Kit |